Protein-based Engineered Nanostructures

Abstract

"This book is devoted to the engineering of protein-based nanostructures and nanomaterials. One key challenge in nanobiotechnology is to be able to exploit the natural repertoire of protein structures and functions to build materials with defined properties at the nanoscale using "bottom-up" strategies. This book addresses in an integrated manner all the critical aspects that need to be understood and considered to design the next generation of nano-bio assemblies. The book covers first the fundamentals of the design and features of the protein building blocks and their self-assembly illustrating some of the most relevant examples of nanostructural design. Finally, the book contains a section dedicated to demonstrated applications of these novel bioinspired nanostructures in different fields from hybrid nanomaterials to regenerative medicine. This book provides a comprehensive updated review of this rapidly evolving field"--Publisher's description. Protein design for nanostructural engineering: general aspects / Tijana Z. Grove, Aitziber L. Cortajarena -- Designed protein origami / Igor Drobnak, Ajasja Ljubetič Helena Gradišar, Tomaž Pisanski, Roman Jerala -- Two-dimensional peptide and protein assemblies / Elizabeth Magnotti, Vincent Conticello -- Designed repeat proteins as building blocks for nanofabrication / Sara H. Mejias, Antonio Aires, Pierre Couleaud, Aitziber L. Cortajarena -- Assembly, engineering and applications of virus-based protein nanoparticles / Mauricio G. Mateu -- Dynamic and active proteins: biomolecular motors in engineered nanostructures / Marisela V̌lez -- Natural composite systems for bioinspired materials / Joseph A. Frezzo, Jin Kim Montclare PhD -- Protein-based hydrogels for tissue engineering / Ashley C. Schloss, Danielle M. Williams, Lynne J. Regan -- Design of self-assembling protein-polymer conjugates / Nathan A. Carter, Xi Geng, Tijana Z. Grove -- Design of redox-active peptides: towards functional materials / Dayn Joseph Sommer, Rafael Alcala-Torano, Zahra Bahrami Dizicheh, Giovanna Ghirlanda -- S-layer-based nanocomposites for industrial applications / Johannes Raff, Sabine Matys, Matthias Suhr, Manja Vogel, Tobias Günther [and others] -- Protein design for nanostructural engineering: concluding remarks and future directions / Tijana Z. Grove, Aitziber L. Cortajarena.