Synthesis of side-chain-substituted ifosfamide analogs

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Abstract

Three analogs of the cytostatic drug ifosfamide incorporating 1-methyl-2-chloroethyl side chains were designed and prepared as an attempt to obtain drugs of lower toxicity.

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Paci, A., Guillaume, D., & Husson, H. P. (2001). Synthesis of side-chain-substituted ifosfamide analogs. Journal of Heterocyclic Chemistry, 38(5), 1131–1134. https://doi.org/10.1002/jhet.5570380517

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