Isolated discrete upper septal thickening in a non-referral cat population of senior and young cats

Abstract

Introduction/objectives: Discrete upper septal thickening (DUST) is a phenotype of elderly people. The cardiac phenotype in senior cats has been incompletely described. We aimed to characterize the echocardiographic phenotype of senior cats, specifically to determine prevalence of DUST and hypertrophic cardiomyopathy (HCM). Animals: One hundred and forty-nine healthy, normotensive cats. Materials and methods: Prospective cross-sectional study. Senior (≥nine years) and young ( <0.0001) and higher interventricular septum ratio (1.4 (1.2–2.0) vs. 1.0 (0.7–1.8)). Univariable analysis showed decreased odds of DUST with greater AoSA (OR 0.9, p<0.0001), age was not associated with DUST. Twenty-nine senior cats had HCM (28.4%). Discussion/conclusions: Prevalence of DUST was 12%. There was no association between age and DUST. Smaller/steeper AoSA was the main factor associated with DUST. There was a high prevalence of HCM in this senior population.