Efeitos da cisplatina em cobaias: histologia coclear e genotoxidade

  • Franceschi C
  • Tochetto T
  • Silveira A
  • et al.
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Abstract

Cisplatin causes changes in cochlear histology, such as the loss of the normal micro-cytoarchitecture of the organ of Corti, and reduction of neurons of the spiral ganglion with cell alterations, however, DNA damage was not detected.

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Franceschi, C. M. de, Tochetto, T., Silveira, A. F. da, Fantinel, M. R., & Algarve, T. D. (2011). Efeitos da cisplatina em cobaias: histologia coclear e genotoxidade. Brazilian Journal of Otorhinolaryngology, 77(6), 728–735. https://doi.org/10.1590/s1808-86942011000600009

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