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Leptin-Replacement Therapy for Lipodystrophy

  • Oral E
  • Simha V
  • Ruiz E
  • et al.
New England Journal of Medicine (2002) 346(8) 570-578
DOI: 10.1056/nejmoa012437
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Abstract

The adipocyte hormone leptin is important in regulating energy homeostasis. Since severe lipodystrophy is associated with leptin deficiency, insulin resistance, hypertriglyceridemia, and hepatic steatosis, we assessed whether leptin replacement would ameliorate this condition.

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APA

Oral, E. A., Simha, V., Ruiz, E., Andewelt, A., Premkumar, A., Snell, P., … Garg, A. (2002). Leptin-Replacement Therapy for Lipodystrophy. New England Journal of Medicine, 346(8), 570–578. https://doi.org/10.1056/nejmoa012437

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