Gold nanoparticles were functionalized with a synthetic polypeptide, de novo-designed to associate with a charge complementary linker polypeptide in a folding-dependent manner. A heterotrimeric complex that folds into two disulphide-linked four-helix bundles is formed when the linker polypeptide associates with two of the immobilized peptides. The heterotrimer forms in between separate particles and induces a rapid and extensive aggregation with a well-defined interparticle spacing. The aggregated particles are redispersed when the disulphide bridge in the linker polypeptide is reduced. © 2008 American Chemical Society.
CITATION STYLE
Aili, D., Enander, K., Baltzer, L., & Liedberg, B. (2008). Assembly of polypeptide-functionalized gold nanoparticles through a heteroassociation-and folding-dependent bridging. Nano Letters, 8(8), 2473–2478. https://doi.org/10.1021/nl8014796
Mendeley helps you to discover research relevant for your work.