Abstract
Poly(ε-caprolactone-co L-lactide)s were synthesized at various feed ratios by ring-opening polymerization using tin(II) octanoate as an initiator. The biodegradability of these copolymers was evaluated with both enzymatic and non-enzymatic hydrolyses. The enzymes used were Rhizopus arrhizus, Rhizopus delemar, and Candida cylindracea lipases and hog liver esterase. The hydrolability of these copolymers depends on the polymer composition, and is higher than that of both homopolymers. The hydrolysis products are 6-hydroxycaproic acid, lactic acid, and oligomers.
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CITATION STYLE
Nakayama, A., Arvanitoyannis, I., Kawasaki, N., Hayashi, K., & Yamamoto, N. (1996). Hydrolytic Degradation of Poly(L-Lactide-co-ε-Caprolactone)S. In Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems (pp. 241–242). Springer Japan. https://doi.org/10.1007/978-4-431-65883-2_57
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