Bilateral posterior ischemic optic neuropathy in a patient with severe diabetic ketoacidosis

Abstract

Purpose: To report a case of bilateral posterior ischemic optic neuropathy (PION) in a patient with severe diabetic ketoacidosis (DKA). Design: Observational case report. Participant: A 35-year-old male who suffered bilateral visual loss during a severe episode of DKA. Methods: Neuro-ophthalmological examination, neuroimaging consisting of a CT scan and MRI of the brain and orbits, as well as a MRA of brain vessels. Results: Bilateral PION was diagnosed in a 35-year-old male with no light perception vision, who emerged from a coma caused by severe DKA. The patient developed optic nerve pallor in both eyes 4 weeks after the initial examination. Visual acuity with no light perception in both eyes remained unchanged after 6 months' follow-up. Conclusions: Severe DKA can be complicated by bilateral PION, resulting in total blindness. Copyright © 2011 S. Karger AG, Basel.