We have investigated the regulation of intracellular free calcium in heart muscle using the free acid form of the Ca2+ indicator fura-2 iontophoretically microinjected into rat cardiac trabeculae or ferret papillary muscles. This method shows great promise in elucidating a number of crucial questions in cardiac excitation-contraction coupling.
CITATION STYLE
Backx, P. H., Wei Dong Gao, Azan-Backx, M. D., Marban, E., Allen, D., Somlyo, A., … Kass, D. (1993). Regulation of intracellular calcium in cardiac muscle. In Advances in Experimental Medicine and Biology (Vol. 346, pp. 3–10). Springer Science and Business Media, LLC. https://doi.org/10.1007/978-1-4615-2946-0_1
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