Mesenchymal Stromal Cell (MSC) Therapy for Crohn’s Disease

Abstract

Promising results of MSCs infusion for GI graft versus host disease and fistulizing Crohn’s Disease (CD) have been published. Treatment of Inflammatory Bowel Disease (IBD) requires a comprehensive treatment approach to maintain symptomatic control, improve health-related quality of life measures, and minimize complications from the disease. In this chapter, we will discuss the role of cellular therapies in Crohn's disease. Success of these phase I, II and III trials have set the stage for usage of this novel treatment in combination with other therapies for CD