Background: Hepatitis E Virus (HEV) infection has a poor prognosis among pregnant women from high endemic countries. HEV-prevalence and incidence among pregnant women is unknown in high-income countries such as France. This prospective study was conducted to assess HEV infection in this setting. Findings. An overall HEV prevalence of 7.74% was observed among 315 pregnant women. Seroprevalence was higher in south than in north of France (29.3% vs. 3.6%, p < 0.0001), and women with detectable IgG were older. No IgG seroconversion or IgM detection were observed during pregnancy. Conclusions: Data suggest that HEV infection is a rare occurrence during pregnancy even in regions of western countries with high seroprevalence rates. © 2014 Renou et al.; licensee BioMed Central Ltd.
CITATION STYLE
Renou, C., Gobert, V., Locher, C., Moumen, A., Timbely, O., Savary, J., & Roque-Afonso, A. M. (2014). Prospective study of Hepatitis e Virus infection among pregnant women in France. Virology Journal, 11(1). https://doi.org/10.1186/1743-422X-11-68
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