The Effect of Nano-Cinnamomum Capsule on Blood Glucose, and Lipid Profile in Type 2 Diabetic Male Rats

Abstract

Objective: High blood sugar caused by problems with insulin secretion, action, or both, or insulin resistance characterizes diabetes mellitus. Cinnamon inhibits NF-B signaling. This study examines Nano-effects Cinnamomum's on diabetic rats' HbA1C, fasting blood sugar, and lipid profile. Materials and Methods: The experiment fed rats HFD for 4 weeks. After that, they were injected with 35 mg/kg STZ to cause T2DM. After 4 weeks of Se-NPs and MET, synergistic effects on diabetic complications were examined. We ran molecular and biochemical tests on insulin sensitivity, oxidative mediators, and inflammatory markers. Results: Mean age, BMI, FBG, total cholesterol, triglycerides, LDL, HDL, HbA1c, and sex were the same at the start. Comparing results before and after treatment (p 0.05), the Nano-Cinnamomum group had lower HbA1C, FBG, TG, and BMI. When values before and after treatment were compared, it was clear that HbA1c, eAG, LDL-C, and BMI had changed (p0.05). Conclusion: These results show that Nano-Cinnamomum may lower HbA1c in people with type 2 diabetes. It may also partially lower serum LDL-C and BMI.