Polycystic Ovary Syndrome and Obstructive Sleep Apnea

Abstract

Obstructive sleep apnea (OSA) is a condition associated with morbidity and lower quality of life. It is common in men, but women can also develop OSA, particularly those with polycystic ovary syndrome (PCOS). OSA and PCOS share multiple intersecting pathophysiologic mechanisms including androgen excess, insulin resistance, inflammation, and obesity which amplify the metabolic sequelae of each. Physicians should be vigilant for symptoms of PCOS among women with sleep disorders and be aware of the screening criteria for PCOS. PCOS women in turn should be queried for symptoms of sleep disordered breathing or non-restorative sleep and referred promptly for OSA evaluation if symptomatic.