Socio-Demographic Factors and Their Correlation with the Severity of Major Depressive Disorder: A Population Based Study

Abstract

Objective: Genetic and neurobiological factors are considered to be the major causes of major depressive disorder (MDD). However, over last few years study results revealed that socio-demographic factors contribute a significant role in abnormal functional activity and recognized as major causative factors to the pathogenesis and severity of MDD. The aim of this study was to assess the socio-demographic characteristics of Bangladeshi MDD patients and to discover their role on the severity of disease. Material and Methods: A retrospective review of the case notes of psychiatry outpatients at Bangabandhu Sheikh Mujib Medical University (BSMMU) was carried out between Sep-Nov 2016. A total of 234 MDD patients (aged 18 to 60 years) were randomly recruited. Relevant information was obtained by collection of prescription details from the patients or their relatives by face to face interview. Results: Mean age and body mass index (BMI) were found 34.734 years (SEM ± 0.842) and 22.014 kg/m2 respectively. Among all respondents, 56% (133) were male and 44% (106) were female where mean income was 26.84 KBDT (Kilo Bangladeshi Taka) (SEM ± 0.749). Roughly 46% (111) patients were found to be below secondary level of education. Married people (56%) had a tendency to develop depression compare to unmarried people (36%). Urban residents (64%) are more prone to suffer from depression than rural residents (36%). There was mild depression in 28% (68), moderate in 37% (157), and severe in 14% (34) patients. Correlation analysis shows that age, sex, marital status, education, family income, and area of residence (p-values 0.004, 0.001, 0.000, 0.011, 0.000 and 0.000, respectively) are associated with the severity of disease.