Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumor

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Abstract

Chimeric-antigen receptor T (CAR-T) cell therapy has been researched in the clinical. However, CAR-T cell therapy for solid tumor is faced with lots of challenges such as cytokine storm, how to find the specific antigen and limitation of microenvironment of tumor. In this review, we will discuss the research of CAR-T cell therapy for solid tumors of digestive system, and possible solutions and future direction.

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Ling, H. (2020). Chimeric-antigen receptor T (CAR-T) cell therapy for solid tumor. In IOP Conference Series: Materials Science and Engineering (Vol. 768). Institute of Physics Publishing. https://doi.org/10.1088/1757-899X/768/5/052051

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