Background and Objectives: The coronary artery disease reporting and data system (CAD-RADS) is intended to standardize the reporting of CCTA and the subsequent management guidelines of CAD. The present study was conducted to investigate the validation of CAD-RADS and the application of coronary calcium grading in CAD management. Patients and Methods: The current study is a single-center prospective study that involved 177 participants with chest pain who were submitted to coronary CT angiography (CCTA). Two reviewers independently assessed CCTA results and gave each patient a CAD-RADS category. The reference standard for determining the clinical utility of CAD-RADS was invasive coronary angiography (ICA). The inter-reviewer agreement (IRA) was tested using the intra-class correlation (ICC). Results: The study enrolled 111 cases with non-significant CAD and 66 cases with significant CAD based on ICA findings. According to the reviewer, the CAD-RADS had a sensitivity, specificity, and accuracy of 90.9 to 100%, 89.2 to 94.6%, and 93.16 to 93.2%, respectively, for predicting severe CAD. The IRA for CAD-RADS categories was excellent (ICC = 0.960). The best cut-off value for predicting severe CAD was CAD-RADS > 3. Significant relation between Ca and severe CAD (p<0.001) was detected. Conclusion: The current study provides a good understanding of CAD-RADS as a standard tool with high diagnostic accuracy.
CITATION STYLE
Ebaid, N. Y., Khalifa, D. N., Ragheb, A. S., Abdelsamie, M. M., & Alsowey, A. M. (2021). Validation of coronary artery disease reporting and data system (CAD-RADS) and application of coronary artery calcium data and reporting system (CAC-DRS) as new standardized tools in the management of coronary artery disease patients. International Journal of General Medicine, 14, 7503–7514. https://doi.org/10.2147/IJGM.S336662
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