Statin use is not associated with reduced risk of skin cancer: A meta-analysis

Abstract

Background:There is contradictory evidence about the association between statin and skin cancer.Methods:Literature search in PubMed and Web of Science was undertaken up to June 2013. Pooled relative risk (RR) estimates and 95% confidence intervals (CIs) were calculated.Result:A total of 21 articles with 29 studies were identified. No association was found between statin and skin cancer among neither melanoma (RR, 0.94; 95% CI, 0.85-1.04) nor non-melanoma skin cancer (RR, 1.03; 95% CI, 0.90-1.19).Conclusion:Our meta-analysis does not support a potential role of statin use in the prevention of skin cancer. © 2014 Cancer Research UK.