Biocatalytic Reduction Reactions from a Chemist's Perspective

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Abstract

Reductions play a key role in organic synthesis, producing chiral products with new functionalities. Enzymes can catalyse such reactions with exquisite stereo-, regio- and chemoselectivity, leading the way to alternative shorter classical synthetic routes towards not only high-added-value compounds but also bulk chemicals. In this review we describe the synthetic state-of-the-art and potential of enzymes that catalyse reductions, ranging from carbonyl, enone and aromatic reductions to reductive aminations.

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Hollmann, F., Opperman, D. J., & Paul, C. E. (2021, March 8). Biocatalytic Reduction Reactions from a Chemist’s Perspective. Angewandte Chemie - International Edition. Wiley-VCH Verlag. https://doi.org/10.1002/anie.202001876

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