Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity

27Citations
Citations of this article
27Readers
Mendeley users who have this article in their library.
Get full text

Abstract

Chronic elevation of the sympathetic nervous system has been identified as a major contributor to the complex pathophysiology of hypertension, states of volume overload - such as heart failure - and progressive kidney disease. It is also a strong determinant for clinical outcome. This review focuses on the central role of the kidneys in the pathogenesis of sympathetic hyperactivity. As a consequence, renal denervation may be an attractive option to treat sympathetic hyperactivity. The review will also focus on first results and the still remaining questions of this new treatment option.

Cite

CITATION STYLE

APA

Vink, E. E., & Blankestijn, P. J. (2012). Evidence and consequences of the central role of the kidneys in the pathophysiology of sympathetic hyperactivity. Frontiers in Physiology, 3 FEB. https://doi.org/10.3389/fphys.2012.00029

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free