Exosome-dependent intercellular communication is an emerging signaling mechanism involved in tissue repair and regeneration. Now in this issue of Cell Stem Cell, Fry et al. (2016) show that muscle stem cells communicate with fibrogenic cells by exosomal trafficking of microRNA-206 to regulate extracellular matrix deposition and muscle tissue remodeling.
Spinazzola, J. M., & Gussoni, E. (2017, January 5). Exosomal Small Talk Carries Strong Messages from Muscle Stem Cells. Cell Stem Cell. Cell Press. https://doi.org/10.1016/j.stem.2016.12.009