High-level aminoglycoside resistance in the beta-hemolytic group G Streptococcus isolate BM2721

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Abstract

The beta-hemolytic group G Streptococcus clinical isolate BM2721 was resistant to high levels of aminoglycosides by synthesis of AAC(6')-APH(2''), APH(3')-III, and ANT(6) modifying enzymes. The corresponding genes were found to be adjacent as the result of a recombination event between Tn4001 and Tn5405, two transposons originating in staphylococci.

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Galimand, M., Lambert, T., Gerbaud, G., & Courvalin, P. (1999). High-level aminoglycoside resistance in the beta-hemolytic group G Streptococcus isolate BM2721. Antimicrobial Agents and Chemotherapy, 43(12), 3008–3010. https://doi.org/10.1128/aac.43.12.3008

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