The birth of the Epitranscriptome: deciphering the function of RNA modifications

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Abstract

Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.

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Saletore, Y., Meyer, K., Korlach, J., Vilfan, I. D., Jaffrey, S., & Mason, C. E. (2012). The birth of the Epitranscriptome: deciphering the function of RNA modifications. Genome Biology, 13(10), 175. https://doi.org/10.1186/gb-2012-13-10-175

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