Evaluation of Antibacterial Activity of Iron Oxide Nanoparticles Synthesis by Extracellular Lactobacillus against Pseudomonas Aeruginosa

Abstract

This study aimed to demonstrate the biosynthetic process of iron oxide nanoparticles (Fe2O3-NPs) by using extracellular components produced by environmental isolates of Lactobacillus plantarum as reducing and stabilizing agents studied in the laboratory of the university of Baghdad. Add 1 g of iron sulfate to 10 mL of extracellular nanoparticles for synthesis. Biosynthetic Fe2O3 nanoparticles have broad application prospects in catalysis, biosensing, anticancer, and biomedicine. Optimal conditions for synthesizing Fe2O3 were investigated using UV-VIS, AFM, XRD, FT-IR, and FE-SEM techniques. The UV-VIS wavelength of NPs within the nanoclusters. Susceptibility testing of P. aeruginosa showed resistance to tetracycline, trimethoprimsulfamethoxazole, ceftazidime, and chloramphenicol, whereas sensitive to Amikacin, Norfloxacin, Meropenem, and Ciprofloxacin and the effect of Fe2O3 NPs from extracellular component on bacteria Pseudomonas aeruginosa on an inhibition zone 18 mm.