Abstract
A rational approach to delivery and target TRH analogs to the CNS was demonstrated to increase CNS effect significantly in an animal model. The evolution of this strategy clearly highlights the importance of controlling transport and metab. in peptide-based drug design. [on SciFinder (R)]
Cite
CITATION STYLE
APA
Prokai, L., Prokai-Tatrai, K., Wu, W.-M., Wu, J., Ouyang, X., Kim, H.-S., … Bodor, N. (2005). Brain delivery and targeting of thyrotropin-releasing hormone analogs by covalent packaging and sequential metabolism. In Peptides Frontiers of Peptide Science (pp. 834–836). Kluwer Academic Publishers. https://doi.org/10.1007/0-306-46862-x_363
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