LC/MS Data Processing for Label-Free Quantitative Analysis

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Abstract

In this chapter, we describe the use of SuperHirn and MSight, two complementary tools developed to the processing of label-free LC/MS data in view of the quantitation of proteomics samples. While MSight is mainly dedicated to the visualisation and navigation into LC/MS data, SuperHirn is specialised in peak detection, normalisation and alignment of LC/MS runs. These two tools can be used in a complementary way and one of the possible usages is described here.

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Palagi, P. M., Müller, M., Walther, D., & Lisacek, F. (2011). LC/MS Data Processing for Label-Free Quantitative Analysis. In Methods in Molecular Biology (Vol. 696, pp. 369–377). Humana Press Inc. https://doi.org/10.1007/978-1-60761-987-1_24

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