Identification of N-glycosylation sites with sequence and structural features employing random forests

Abstract

N-Glycosylation plays a very important role in various processes like quality control of proteins produced in ER, transport of proteins and in disease control.The experimental elucidation of N-Glycosylation sites is expensive and laborious process. In this work we build models for identification of potential N-Glycosylation sites in proteins based on sequence and structural features.The best model has cross validation accuracy rate of 72.81%. © 2009 Springer-Verlag Berlin Heidelberg.