Testing the sensitivity of conjunctival swabs from confirmed covid-19 patients

0Citations
Citations of this article
20Readers
Mendeley users who have this article in their library.

Abstract

Objective: To investigate the incidence of COVID-19 viral RNA in the conjunctiva of patients priorly confirmed to have COVID-19, using a conjunctival swab and to determine swab sensitivity. Methods: This cross-sectional study enrolled patients who tested positive for COVID-19 with PCR via nasopharyngeal swabs. Conjunctival swabs were collected for each patient and subjected to RT-PCR assay. Demographic data and clinical history of patients were investi-gated and analysed. Results: In this study, 4.9% of the patients tested positive with conjunctival swabs for COVID-19; 29.9%, 28.7%, 20.1%, and 12.2% of the patients had fever, shortness of breath, cough, and red eye, respectively. Among all patients, 18.9% and 73.2% had a history of traveling and contact with positive COVID-19 cases, respectively. There were significant correlations between the conjunctival results and diabetes (P=0.049) and hypertension (P=0.002). Traveling was a risk factor for positive conjunctival swab testing (P=0.016). The sensitivity of the conjunctival swab was 4.8%. Conclusion: Among all positive cases of COVID-19, a small percentage had positive results when tested using a conjunctival swab. Conjunctival swabs have very low sensitivity for the detection of COVID-19. However, tears could still be a mode of disease transmission, especially from patients to eye care specialists.

Cite

CITATION STYLE

APA

Hadrawi, M., Malak, M., Almahmoudi, F., Mogharbel, A., Rozy, O., Hanafi, S., … Alzahrani, K. (2021). Testing the sensitivity of conjunctival swabs from confirmed covid-19 patients. Clinical Ophthalmology, 15, 2489–2496. https://doi.org/10.2147/OPTH.S313721

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free