Abstract
The TVRM program at The Jackson Laboratory (JAX) is tailored to provide genetically defined models of vision-associated diseases to the Research Community. It utilizes chemical mutagenesis to generate mutations, and indirect ophthalmoscopy, slit lamp biomicroscopy, fundus photography and electroretinography (ERG) to screen for disease phenotypes. To date 60 ocular models have been identified (Won et al. 2010). Three new mutant alleles that lead to retinal degeneration are described herein. © 2012 Springer Science+Business Media, LLC.
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Won, J., Shi, L. Y., Hicks, W., Wang, J., Naggert, J. K., & Nishina, P. M. (2012). Translational vision research models program. In Advances in Experimental Medicine and Biology (Vol. 723, pp. 391–397). https://doi.org/10.1007/978-1-4614-0631-0_50
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