Liver cirrhosis is anatomically defined as a diffuse disruption of the normal architecture of the liver with fibrosis and nodule formation. It is the end result of fibrogenesis caused by chronic liver injury. The anatomical architecture is the same with any etiology: continuous inflammation or hepatocyte damage causes fibrogenesis, and fibers extend from central or portal area, and finally fibrous septa is completely formed to surround regenerative nodules. Thus liver cirrhosis is characterized with hepatocyte dysfunction and portal hypertension.
CITATION STYLE
Takahara, T., Iwai, M., & Tsui, W. M. S. (2019). Liver Cirrhosis. In Diagnosis of Liver Disease, Second Edition (pp. 61–73). Springer Singapore. https://doi.org/10.1007/978-981-13-6806-6_6
Mendeley helps you to discover research relevant for your work.