Discovery of the γδ TCR: Act II

Abstract

In 1986, the discovery of the TCR ([1][1]–[3][2]), the cloning of the α and β genes that encode it ([4][3]–[9][4]), and various findings regarding TCR function were still recent events. The latter included the role of the “T3 glycoprotein” (CD3 complex) in TCR signal transduction, its