Abstract
Lobular carcinoma in situ (LCIS) is a high-risk indicator lesion for and a non-obligate precursor of the development of invasive breast carcinoma. Loss of E-cadherin is the hallmark pathological feature of lobular entities. Effective clinical management of LCIS requires good communication between the radiologist, surgeon, pathologist, and medical oncologist and entails surgical excision, subsequent surveillance, and systemic and surgical strategies to reduce the risk of future invasive cancer.
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McAuliffe, P., & McAuliffe, P. (2015). Lobular Carcinoma In Situ. In Breast Disease: Diagnosis and Pathology (Vol. 1, pp. 123–129). Springer International Publishing. https://doi.org/10.1007/978-3-319-22843-3_6
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