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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To determine the efficacy and safety of a 6-thioguanine nucleotide (6-TGN) metabolite-based dosing strategy for maintenance of remission using azathioprine or mercaptopurine in Crohn's disease and ulcerative colitis.
Mateen, B. A., Patel, M., Akobeng, A. K., Gordon, M., & Hayee, B. (2021). 6-thioguanine nucleotide monitoring in azathioprine and mercaptopurine monotherapy for the treatment of inflammatory bowel disease. Cochrane Database of Systematic Reviews, 2021(10). https://doi.org/10.1002/14651858.CD014795
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