β-nitroacrylates as useful building blocks for the synthesis of alkyl indole-2-carboxylates

Alessandro Palmieri; Serena Gabrielli; Raimondo Maggi; Roberto Ballini

Journal ArticleOPEN ACCESS

β-nitroacrylates as useful building blocks for the synthesis of alkyl indole-2-carboxylates

Palmieri A
Gabrielli S
Maggi R
et al.

Synlett (2014) 25(1) 128-132

DOI: 10.1055/s-0033-1340075

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Abstract

Polyfunctionalized alkyl indole 2-carboxylates can be easily synthesized starting form β-nitroacrylates and o-bromoanilines through an addition-elimination process followed by an intramolecular palladium-catalyzed Heck reaction. © Georg Thieme Verlag Stuttgart · New York.

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Palmieri, A., Gabrielli, S., Maggi, R., & Ballini, R. (2014). β-nitroacrylates as useful building blocks for the synthesis of alkyl indole-2-carboxylates. Synlett, 25(1), 128–132. https://doi.org/10.1055/s-0033-1340075

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β-nitroacrylates as useful building blocks for the synthesis of alkyl indole-2-carboxylates

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Practical methodologies for the synthesis of indoles

Catalytic functionalization of Indoles in a new dimension

Marine natural products

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