CLINICAL PRESENTATION OF POLYCYSTIC OVARY SYNDROME AMONG SAUDI ARABIAN WOMEN – JEDDAH – SAUDI ARABIA.

Abstract

Background: Polycystic ovary (PCO) is a highly variable condition with a wide array of presentations. The Polycystic ovary syndrome should meet at least two of the following three criteria: oligo-or anovulation; clinical and/or biochemical signs of hyperandrogenism; polycystic ovaries on ultrasound. The prevalence of PCO is largely unknown in Saudi Arabia. Objectives: The aim of this study was to investigate the reproductive hormones levels in patients with polycystic ovary syndrome (PCOS) in addition to the effect of age and body mass index (BMI) on the hormonal findings ,ultrasound and to determine the clinical, biochemical, and etiologic features of hirsutism in Saudi females. Methodology: A cross sectional study has been conducted among total of 183 patients diagnosed with PCOS had been assessed clinically along with measuring the level of reproductive hormones in Obstetrics and Gynecology Clinic at King Abdul-Aziz hospital and oncology center in Jeddah, Saudi Arabia, between June 2015 and June 2016. Conclusion: Elevated levels of luteinizing hormone / Follicle stimulating hormone LH/FSH and testosterone and reduced FSH, hormone-binding globulin (SHBG), and progesterone were predictors of PCOS. This was independent of BMI or age. Future studies with larger sample size and data on insulin levels are needed for greater understanding of the manifestations of PCOS in the Saudi population.