Multi-spectral imaging of blood volume, metabolism, oximetry, and light scattering

Abstract

Advances in functional imaging techniques including fMRI, PET, and SPECT have improved our understanding of the relationship between brain activity and brain energy supply. Neurovascular and neurometabolic coupling are critical to supply the energy demands of brain tissue during both normal physiological function and pathological conditions. With the use of multi-spectral imaging techniques, one can simultaneously measure changes in cerebral blood volume, oxyhemoglobin, deoxyhemoglobin, light scattering, and local metabolism during epilepsy.