Evaluation of injectable nucleus augmentation materials for the treatment of intervertebral disc degeneration

12Citations
Citations of this article
29Readers
Mendeley users who have this article in their library.

Abstract

Back pain affects a person's health and mobility as well as being associated with large health and social costs. Lower back pain is frequently caused by degeneration of the intervertebral disc. Current operative and non-operative treatments are often ineffective and expensive. Nucleus augmentation is designed to be a minimally invasive method of restoring the disc to its native healthy state by restoring the disc height, and mechanical and/or biological properties. The majority of the candidate materials for nucleus augmentation are injectable hydrogels. In this review, we examine the materials that are currently under investigation for nucleus augmentation, and compare their ability to meet the design requirements for this application. Specifically, the delivery of the material into the disc, the mechanical properties of the material and the biological compatibility are examined. Recommendations for future testing are also made.

Cite

CITATION STYLE

APA

Culbert, M. P., Warren, J. P., Dixon, A. R., Fermor, H. L., Beales, P. A., & Wilcox, R. K. (2022, February 21). Evaluation of injectable nucleus augmentation materials for the treatment of intervertebral disc degeneration. Biomaterials Science. Royal Society of Chemistry. https://doi.org/10.1039/d1bm01589c

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free