Clinical presentation and therapy of d-Transposition of the great arteries

Abstract

d-Transposition of the great arteries (d-TGA) is the most common form of congenital heart disease that presents with cyanosis in a newborn. The aorta arises from the right ventricle and the pulmonary artery arises from the left ventricle. It constitutes 3.8 % of all congenital cardiac defects. Forty percent of patients with d-TGA have an associated ventricular septal defect. Among patients with d-TGA, 6 % of those with intact ventricular septum and 31 % of those with ventricular septal defect have associated pulmonary stenosis.