Development of an image-guided radiation therapy device for precise irradiation of small animal tumors

Abstract

An image-guided radiation therapy device for small animals such as mice and rats is proposed. The main components of the device are a single-pole metal-ceramic X-ray tube with a voltage range of 10 kV to 225 kV, an amorphous-Silicon flat panel detector, a three dimensional motorized positioning system holding a small animal test-bed, and a radiation protection housing. The final set-up of this device for medical treatment should allow isocentric irradiation through complete 360 deg rotation of the radiation source and use of cone beam CT techniques. Development of a treatment planning software is also anticipated. This device is currently being designed and built. © 2009 Springer-Verlag.