Is T Cell Exhaustion a Treatable Trait in Sepsis?

  • Fish M
  • Swanson C
  • Shankar-Hari M
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Abstract

The immune system is profoundly dysregulated in sepsis with simultaneous hyperinflammation and immunosuppression. One facet of sepsis-related immunosuppression is T cell exhaustion, which is characterized by impaired effector cell function and persistent upregulation...

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Fish, M., Swanson, C. M., & Shankar-Hari, M. (2020). Is T Cell Exhaustion a Treatable Trait in Sepsis? (pp. 271–279). https://doi.org/10.1007/978-3-030-37323-8_22

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