Background: Patients with hypertension continue to have less than optimal blood pressure control, with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of care. With Alberta being the first province in Canada to have independent prescribing by pharmacists, it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists.Methods: The study is a randomized controlled trial of enhanced pharmacist care, with the unit of randomization being the patient. Participants will be randomized to enhanced pharmacist care (patient identification, assessment, education, close follow-up, and prescribing/titration of antihypertensive medications) or usual care. Participants are patients in rural Alberta with undiagnosed/uncontrolled blood pressure, as defined by the Canadian Hypertension Education Program. The primary outcome is the change in systolic blood pressure between baseline and 24 weeks in the enhanced-care versus usual-care arms. There are also three substudies running in conjunction with the project examining different remuneration models, investigating patient knowledge, and assessing health-resource utilization amongst patients in each group.Discussion: To date, one-third of the required sample size has been recruited. There are 15 communities and 17 pharmacists actively screening, recruiting, and following patients. This study will provide high-level evidence regarding pharmacist prescribing. Trial Registration: Clinicaltrials.gov NCT00878566. © 2011 Charrois et al; licensee BioMed Central Ltd.
CITATION STYLE
Charrois, T. L., McAlister, F. A., Cooney, D., Lewanczuk, R., Kolber, M. R., Campbell, N. R. C., … Tsuyuki, R. T. (2011). Improving hypertension management through pharmacist prescribing; The rural alberta clinical trial in optimizing hypertension (Rural RxACTION): Trial design and methods. Implementation Science, 6(1). https://doi.org/10.1186/1748-5908-6-94
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