Confocal and multi-photon imaging of living embryos

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Abstract

By its very nature, developmental biology requires thinking in four dimensions. Not only do embryos change dramatically over time, as the seemingly featureless single-celled zygote is transformed into an embryo with recognizable body axes and organ systems, but this remarkable transformation occurs in three spatial dimensions. The coordinated changes that occur within the developing embryo include carefully orchestrated signaling events, changes in gene expression, and morphogenetic movements, that is, regulated cell divisions and cell movements that sculpt the basic body plan as a recognizable organism emerges. © 2006, 1995, 1989 Springer Science+Business Media, LLC. All rights reserved.

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Hardin, J. (2006). Confocal and multi-photon imaging of living embryos. In Handbook of Biological Confocal Microscopy: Third Edition (pp. 746–768). Springer US. https://doi.org/10.1007/978-0-387-45524-2_43

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