Correlation between bio-impedance analysis and abdominal CT scan to diagnose decreased muscle mass in adult cancer patients

Abstract

mobile phone number. Patient's family were also encouraged to communicate with the team by phone in case of fresh complain and urgency in between. Results: Since last one year, 193 cancer patients were contacted by mobile phone every two weeks to enquire about their difficulties. In 76% of the situation trained social workers could give necessary advice by phone regarding management of their physical symptoms. Moreover, patient's family were really overwhelmed by the emotional support offered by the team over phone. Only 24% of cancer patients has to attend the nodal centre for expert advice from Palliative Care specialists. Conclusions: This novel approach helped: In providing regular physical and emotional support to the patients and their families. In significantly reducing the financial and manpower problems of carrying patients to the nodal units. In improve the quality of life of patients by continuous guidance. More and more team members can take help of this new strategy for better communication and uninterrupted care. Legal entity responsible for the study: The author. Funding: Has not received any funding. Disclosure: The author has declared no conflicts of interest. 436P Assessing the quality of life of Filipino cancer patients: A survey of Filipino oncologists Background: With the advent of personalized medicine, recent clinical trials have placed much emphasis on the OS and PFS of cancer patients. However, several international guidelines also emphasize the need for assessing the Health Related Quality of Life (HRQoL) as part of our holistic approach in the management of cancer patients. This study evaluated the present status of the Filipino oncologists' approach in assessing the quality of life of cancer patients. Methods: This was a cross-sectional study that utilized a survey questionnaire. Participants included physicians in the care of the cancer patient (consultants & trainees)-medical, surgical, radiation, gynecologic oncologists, and hematologists, who were contacted via email through the database of their respective societies, and personally during scientific meetings / conferences. Descriptive and multivariate analysis were used to analyze the data. Results: 312 oncologists participated. 96% reported that HQRoL assessment was important for clinical work, however 58% perceived HRQoL to be a vague term; 69% agreed that verbal HRQoL assessments were generally enough, and 39% reported that their patients did not accept HRQoL questionnaires. Furthermore, 78% did not know which HRQoL assessment tool to use, and that the questionnaires were too extensive and too lengthy for routine use; 55% reported that they did not feel sufficiently trained to assess HRQoL. About 89.42% reported that they will be more confident if local HRQoL assessment guidelines will be present, and 92.95% agreed to the use of a unified HRQoL assessment tool for Filipino cancer patients. Conclusions: Filipino oncologists perceived HRQoL patient assessments to be important in clinical practice. However, majority did not know which tool to use and did not feel sufficiently trained to assess HRQoL. The creation of a practice guideline that would facilitate the use of a unified HRQoL assessment tool (containing 5-15 questions) for Filipino cancer patients will be explored. Legal entity responsible for the study: The Authors. Funding: Has not received any funding. Disclosure: All authors have declared no conflicts of interest. 437P Correlation between bio-impedance analysis and abdominal CT scan to diagnose decreased muscle mass in adult cancer patients Background: Sarcopenia, characterized by a decline of skeletal muscle plus low muscle strength and/or physical performance, has emerged to be an important prognostic factor for advanced cancer patients. Sarcopenia is diagnosed if there is decreased muscle mass and either decreased muscle function or physical activity. The diagnostic tools for evaluating muscle mass in cancer patients was using muscle index derived from abdominal CT scan. However, the practicability of using CT scan for screening decreased muscle mass has been questioned. Until know there is limited data diagnostic value of Bio-impedance analysis (BIA) in cancer patients. The aim of this study is to know the correlation between BIA and abdominal CT scan to diagnose decreased muscle mass in cancer patients. Methods: This cross-sectional study included adult cancer patients who underwent abdominal CT scans in purpose for diagnostic. BIA was performed in the same day when CT-scan was performed. CT-scans was analyzed using special software. BIA was performed using standing-posture 2-electrode BIA device BC-418 (BIA, Tanita Corp, Tokyo, Japan). Height adjusted appendicular skeletal muscle mass (ASM) was calculated from BIA. Height adjusted skeletal muscle Index (SMI) was performed from a single cross-sectional CT image (slice) at third lumbar (L3) for abdominal skeletal muscle area. We calculated Pearson's r correlation coefficient between two parameters. Results: A total of 39 patients were included. Twenty-eight (71.8%) patients were female. The mean of age was 51.18 þ13.83 years old. Several type of cancer such as breast, lung, gastrointestinal and genitourinary cancer were included. Eleven (28.2%) patients were in advanced stage. Mean of height adjusted BIA was 6.60 þ 0.98 kg/m2. Mean of height adjusted muscle mass was 42.25 þ 7.57 cm2/m2. BIA and CT-derived muscle were moderately correlated (r ¼ 0.72, p < 0.001). Conclusions: This study showed that BIA-and CT-derived muscle mass was moderately correlated in adult cancer patients. Further research is needed to confirm this result.