Drug-induced Liver Injury in a Patient with Coronavirus Disease 2019: Potential Interaction of Remdesivir with P-Glycoprotein Inhibitors

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Abstract

We report a case of a man with COVID-19 who developed acute hepatotoxicity related to remdesivir with probable interaction of P-glycoprotein (P-gp) inhibitors. Until further details on this interaction become available, we recommend physicians to be cautious with the prescription of P-gp inhibitors in patients receiving remdesivir therapy.

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APA

Leegwater, E., Strik, A., Wilms, E. B., Bosma, L. B. E., Burger, D. M., Ottens, T. H., & Van Nieuwkoop, C. (2021). Drug-induced Liver Injury in a Patient with Coronavirus Disease 2019: Potential Interaction of Remdesivir with P-Glycoprotein Inhibitors. Clinical Infectious Diseases, 72(7), 1256–1258. https://doi.org/10.1093/cid/ciaa883

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