Triadin-1, encoded by TRDN, is an important component of the calcium release unit (CRU) in the sarcoplasmic reticulum of cardiac myocytes, interacting both with ryanodine receptors and calsequestrin. This article reviews evidence substantiating a link between TRDN mutations and potentially fatal ventricular arrhythmias.
CITATION STYLE
Hancox, J. C., James, A. F., Walsh, M. A., & Stuart, A. G. (2017). Triadin mutations - a cause of ventricular arrhythmias in children and young adults. Journal of Congenital Cardiology, 1(1). https://doi.org/10.1186/s40949-017-0011-9
Mendeley helps you to discover research relevant for your work.