Bronchiolitis obliterans in systemic lupus erythematosus: Beneficial effect of intravenous cyclophosphamide

Abstract

A 49 year old white woman with systemic lupus erythematosus and bronchiolitis obliterans was treated with prednisone (1 mg/kg daily), which led to a transitory improvement in pulmonary status. Cyclophosphamide was then added-A mg/kg daily intravenously for five days, then 2 mg/kg daily orally-and this was followed by a dramatic and prolonged improvement.