Ocular manifestations in patients who had malnutrition in the first six months of life

Abstract

Purpose: To investigate possible ophthalmologic alterations in patients who had severe malnutrition during the first six months of life. Methods: 182 eyes of 91, 2 to 11-year-old, children who had severe malnutrition during the first six months of life (study group) were analyzed. As a control group 88 children selected according to similar characteristics of age, gender, demographic and economic conditions were included. Results: In the study group, a higher frequency of children with visual acuity from 0.3 to 0.1 and less than 0.1 (11.5% versus 0.7% - p<0.0001) was observed. There was a higher frequency of astigmatism and myopia in the study group. A higher frequency of astigmatism of one diopter or more in the study group (p<0.0001) was also observed. The fundoscopic alterations were pale optic nerve (2.2%), increased disc cup (4.4%), increased vascular tortuosity (6.6%), alteration of retina color (13.2%) and retinal pigment epithelium cell atrophy (12.0%). Conclusions: The present data support the concept that early malnutrition interferes in the individual's visual health. Further studies are necessary to establish a more precise cause-effect relationship.