Orofacial pain - A presenting symptom of bisphosphonate associated osteonecrosis of the jaws

Abstract

Osteonecrosis of the jaws (ONJ) associated with bisphosphonate therapy is being reported with increasing frequency all over the world. Pain may be the presenting symptom commonly associated with intra-oral bone exposure. The aetiology of this therapeutic complication is still not well understood. Three cases are presented and the management of the condition is discussed. © 2007 Nature Publishing Group.