Variogram based estimator of fractal dimension for the analysis of cell nuclei from the papanicolaou smears

Abstract

The aim of cervical screening is detection of potentially pre-cancerous and cancerous changes in the endocervical canal of female reproductive system. There are many Fractal Dimension (FD) that are important for the computer assisted analysis of the texture of cell nuclei. The best method is the algorithm that process all pixels of the cell nuclei, not limited by the constraints. Variogram algorithm is proposed for cell nuclei classification (correct and atypical cell classes). Obtained results shows that variogram and cell nuclei size are important for the automatic classification of cell nuclei. © 2013 Springer-Verlag.