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P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary

  • Ralph A
  • Meyer A
  • Sirota R
  • et al.
Clinical Case Reports (2015) 3(10) 817-818
DOI: 10.1002/ccr3.338
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Abstract

The prognostic utility of HPV in oropharyngeal squamous cell carcinoma ( OPSCC ) and non‐ OPSCC as has been well documented. Currently, a standardized IHC scoring system does not exist and is needed to define HPV positivity. We have recently seen a patient that provides a caution in using p16 status as a diagnostic aid.

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Ralph, A., Meyer, A., Sirota, R., & Hooberman, A. (2015). P16 and HPV discordance in metastatic carcinoma of cervical lymph nodes of unknown primary. Clinical Case Reports, 3(10), 817–818. https://doi.org/10.1002/ccr3.338

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