Naturally occurring 1,1'-trimethylenebisuracil from the marine sea hare Dolabella auricularia

Abstract

Dedicated to Prof. H. Duddeck, Department of Chemistry, Hannover University, Germany for his excellent contribution in the structure elucidation of natural products. From the marine sea hare Dolabella auricularia, along with the RNA nucleobase, uracil (2), an unusual bisuracil analogue, 1,1'-trimethylenebisuracil (1) has been isolated and its structure established by extensive 1D NMR, 2D NMR and IR spectroscopic and mass spectrometric data.